The American College of Medical Genetics and Genomics (ACMG) recommends that pathogenic and likely pathogenic variants identified in a specific subset of genes associated with medically actionable, inherited disorders be reported for all patients undergoing exome or genome sequencing.
Please refer to the latest version of the ACMG recommendations for reporting of secondary findings in clinical exome and genome sequencing for complete details of the genes and associated genetic disorders.
Secondary findings will be included in all exome and genome sequencing reports, unless a patient opts-out of receiving this information in the Patient Consent section of the test requisition form.
The presence of any secondary finding(s) reported for the patient will be provided for all relatives included as part of the patient’s test. GeneDx does not conduct an independent evaluation of secondary findings in relatives.
Relatives have the ability to opt-out of receiving secondary findings. Secondary findings will be confirmed by an alternate test method when needed.