Monday, May 27 is Memorial Day. Our lab and all support services will be closed. Kit orders placed on May 27 will be sent on May 28, and all in-transit patient samples will be held by the carrier and received on May 28. If you need assistance, please leave a message at (888) 729-1206 or and we will respond when we return on May 28.

Hereditary Cancer Testing

Go Deeper, See More

Extensive and flexible hereditary cancer testing options to aid in personalized medical management.

A legacy of expertise 

Our expertise in hereditary cancer began over a decade ago, founded by cancer-focused genetic counselors and molecular geneticists who wanted to lead genetic testing in clinical oncology. Today, we’re known for our expertise utilizing a variety of technologies and specimen types, our dedicated clinical service liaison genetic counseling team, trusted variant classification process, and reliable turnaround times. 

We offer an extensive and flexible hereditary cancer testing menu, from Sanger to exome-based testing, for multiple cancer types, including tumor-type specific, and gene or variant specific options, so you can select the most appropriate test for your patient. 

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Support, every step of the way

Genetic testing for hereditary cancer can provide actionable information that enables treatment guidance for a current cancer diagnosis or risk reduction for future cancers. This means that choosing the right test for the patient is important. 

Our team of certified genetic counselors is available via email or phone to support healthcare providers through the genetic testing process. We provide you with tools for identifying at-risk patients, educational materials, and support in selecting the most beneficial test. Once testing is complete, we can assist you with the interpretation of test results and their implications for your patient and their family. 

We’re Here When You Need Us


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We have a dedicated clinical service liaison genetic counseling team, who specialize in hereditary cancer, that can be reached quickly by phone or email.

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A genetic counselor or genetic counseling assistant reviews all genetic test orders for hereditary cancer. As needed, the clinical team will follow up with the provider about test selection, specimen type, or other information.

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Our rigorous variant classification process is backed by genetic counselors and molecular geneticists who specialize in hereditary cancer.  We review clinical history, family history, test order, specimen type, and more.

Rapid test results and reliable turnaround times

Test results are available in 8-10 days* for BRCA1/2 and in 2-3 weeks* for panels, allowing for quicker integration of genetic information into your patients’ care.  

* Reporting times are estimated, but could be extended in situations outside GeneDx’s control.

Flexible specimen options

We offer testing on several different specimen types including blood, buccal swabs, and cultured fibroblasts. 

GeneDx has the ability to culture fibroblasts in house, making genetic testing for patients with certain hematological malignancies or a history of a bone marrow/stem cell transplant easier. 

Buccal kits can be sent directly to patients for easy at-home specimen collection. 

Who should be considered for genetic testing for hereditary cancer?

Medical History

  • Cancer diagnosed at a young age
  • Multiple primary cancers diagnosed in one person, such as two separate colorectal cancers or breast and ovarian cancer
  • Ovarian, pancreatic, male breast, pheochromocytoma/paraganglioma, or metastatic prostate cancer, regardless of age at diagnosis or family history
  • Tumor testing suggestive of a hereditary cancer syndrome, such as abnormal results from MSI (Microsatellite Instability), IHC (Immunohistochemistry), or somatic sequencing
  • Multiple gastrointestinal polyps
  • MDS (Myelodysplastic syndrome) or AML (Acute myeloid leukemia) diagnosed under the age of 50

Family Medical History

  • Multiple relatives on the same side of the family with the same or related hereditary cancers such as:
    • Breast, ovarian, pancreatic, and/or prostate
    • Colorectal, uterine, ovarian, and/or stomach
  • A genetic variant previously found in a family member that increases the risk for cancer