Brain Tumor Panel

New York
Approved


Genes

APC, CDKN1B, CDKN2A, DICER1, EPCAM, MEN1, MLH1, MSH2, MSH6, NF1, NF2, PMS2, POT1, PTCH1, PTEN, SMARCA4, SMARCB1, SMARCE1, SUFU, TP53, TSC1, TSC2, VHL

Conditions

  • Brain Cancer
  • Benign brain tumors

Clinical Utility

  • A personal or family history of a brain tumor highly associated with a hereditary syndrome (such as: atypical teratoid/rhabdoid tumor (AT/RT), choroid plexus carcinoma, hemangioblastoma, Lhermitte-Duclos Disease).
  • A personal or family history of a brain tumor diagnosed at a young age (≤18 years) along with additional features of a hereditary syndrome.
  • Multiple tumors and/or cancers in one person.
  • Multiple relatives diagnosed with brain tumors and/or related cancers on the same side of the family and spanning multiple generations.

Lab Method

  • Next-Gen Sequencing
  • Deletion/Duplication Analysis
  • Capillary Sequencing

Test Code

T831

CPT Codes*

81404x1, 81405x1, 81406x1, 81407x1

ABN Required

No

Turnaround Time**

3 weeks

Preferred Specimen

2-5 mL Blood - Lavender Top Tube

Alternative Specimen

Buccal Swabs | Extracted DNA

*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

**Reporting times are typical and begin once the sample(s) are received at the GeneDx laboratory, but could be extended in situations outside GeneDx’s reasonable control.