XomeDxSlice Tool

Now Available - NEW XomeDxSlice Xpanded – Custom slice testing with trio analysis for lists >150 genes.

INSTRUCTIONS (AND TIPS)

ENTER GENES BELOW AND CLICK "ADD GENES TO SLICE"

If cutting and pasting from another document, please be sure to list EITHER one gene symbol per line OR enter a comma-separated list.


OR

SEARCH BY GENE SYMBOL OR PHENOTYPE (HPO TERM)

You may also use this search to review average exome sequencing coverage by entering the gene symbol below.

SELECTED GENES FOR YOUR SLICE

What do you want to do?

Place an e-order of this Slice on a specific patient through the GeneDx Portal  
Obtain a Slice ID to order testing with a printed requisition form  
Only email the gene list to myself and/or others at this time  


 
Phenotypes
Uterus didelphys

Select all: Gene symbolChrAvg % covered at 10xLocus TypeNoteOMIMPrevious symbol(s)Phenotype(s)Slice(s)
AXIN116p13.3100%gene with protein product603816Autosomal dominant inheritance; Hepatocellular carcinoma; Heterogeneous; Micronodular cirrhosis; Somatic mutation; Subacute progressive viral hepatitis; Ureteral duplication; Uterus didelphys
DYNC2H111q22.399.78%gene with protein product603297DNCH2Abdominal distention; Abnormal pelvis bone ossification; Abnormality of cardiovascular system morphology; Abnormality of pelvic girdle bone morphology; Abnormality of the clavicle; Abnormality of the metaphysis; Abnormality of the ribs; Abnormality of the sternum; Absent or minimally ossified vertebral bodies; Ambiguous genitalia; Brachydactyly; Cleft upper lip; Cone-shaped epiphysis; Congenital hepatic fibrosis; Cryptorchidism; Depressed nasal bridge; Disproportionate short-limb short stature; Epicanthus; Frontal bossing; Hydronephrosis; Hydrops fetalis; Hypoplasia of penis; Lethal skeletal dysplasia; Long philtrum; Macrocephaly; Micrognathia; Micromelia; Narrow chest; Postaxial hand polydactyly; Renal hypoplasia; Respiratory insufficiency; Short foot; Short palm; Short ribs; Short thorax; Skeletal dysplasia; Urethrovaginal fistula; Uterus didelphys; Wide noseDisorders of Sex Development; Heterotaxy ; Short-Rib Thoracic Dysplasia
HOXA137p15.299.57%gene with protein product142959HOX1J, HOX1Abnormal dermatoglyphics; Autosomal dominant inheritance; Bicornuate uterus; Bifid scrotum; Brachydactyly; Chordee; Clinodactyly of the 5th finger; Delayed ossification of carpal bones; Delayed tarsal ossification; Glandular hypospadias; Hallux varus; Hypoplastic fifth toenail; Hypospadias; Longitudinal vaginal septum; Micropenis; Postaxial hand polydactyly; Proximal placement of thumb; Pseudoepiphyses; Recurrent urinary tract infections; Renal insufficiency; Short 1st metacarpal; Short 2nd toe; Short 5th finger; Short distal phalanx of finger; Short first metatarsal; Short hallux; Shortening of all middle phalanges of the fingers; Small thenar eminence; Synostosis of carpal bones; Ulnar deviation of the 2nd finger; Ureteropelvic junction obstruction; Uterus didelphys; Vesicoureteral refluxDisorders of Sex Development
IFT803q25.3394.79%gene with protein product611177WDR56Abdominal distention; Abnormal pelvis bone ossification; Abnormality of cardiovascular system morphology; Abnormality of pelvic girdle bone morphology; Abnormality of the clavicle; Abnormality of the metaphysis; Abnormality of the ribs; Abnormality of the sternum; Absent or minimally ossified vertebral bodies; Ambiguous genitalia; Autosomal recessive inheritance; Brachydactyly; Broad palm; Cleft upper lip; Cone-shaped epiphysis; Congenital hepatic fibrosis; Cryptorchidism; Depressed nasal bridge; Disproportionate short-limb short stature; Epicanthus; Frontal bossing; Hydronephrosis; Hydrops fetalis; Hypoplasia of penis; Lethal skeletal dysplasia; Long philtrum; Macrocephaly; Mesomelia; Micrognathia; Micromelia; Narrow chest; Postaxial hand polydactyly; Renal hypoplasia; Respiratory insufficiency; Rhizomelia; Short foot; Short metacarpal; Short palm; Short ribs; Short thorax; Skeletal dysplasia; Urethrovaginal fistula; Uterus didelphys; Wide noseShort-Rib Thoracic Dysplasia
WDR349q34.11100%gene with protein product613363Abdominal distention; Abnormal pelvis bone ossification; Abnormality of cardiovascular system morphology; Abnormality of pelvic girdle bone morphology; Abnormality of the clavicle; Abnormality of the metaphysis; Abnormality of the ribs; Abnormality of the sternum; Absent or minimally ossified vertebral bodies; Ambiguous genitalia; Autosomal recessive inheritance; Bell-shaped thorax; Brachydactyly; Cleft upper lip; Cone-shaped epiphysis; Congenital hepatic fibrosis; Cryptorchidism; Depressed nasal bridge; Disproportionate short-limb short stature; Epicanthus; Frontal bossing; Horizontal ribs; Hydronephrosis; Hydrops fetalis; Hypoplasia of penis; Lethal skeletal dysplasia; Long philtrum; Macrocephaly; Micrognathia; Micromelia; Narrow chest; Postaxial hand polydactyly; Recurrent respiratory infections; Renal hypoplasia; Respiratory insufficiency; Short foot; Short long bone; Short palm; Short ribs; Short thorax; Skeletal dysplasia; Thoracic dysplasia; Urethrovaginal fistula; Uterus didelphys; Wide noseShort-Rib Thoracic Dysplasia
WDR352p24.199.89%gene with protein product613602Abdominal distention; Abnormal diaphysis morphology; Abnormal pelvis bone ossification; Abnormal toenail morphology; Abnormality of cardiovascular system morphology; Abnormality of the fingernails; Abnormality of the metaphysis; Abnormality of the pinna; Absent or minimally ossified vertebral bodies; Ambiguous genitalia; Anteverted nares; Autosomal recessive inheritance; Blepharophimosis; Bowing of the long bones; Brachydactyly; Cleft upper lip; Congenital hepatic fibrosis; Craniosynostosis; Cryptorchidism; Cystic hygroma; Depressed nasal bridge; Disproportionate short-limb short stature; Dolichocephaly; Ectodermal dysplasia; Epicanthus; Everted lower lip vermilion; Finger syndactyly; Frontal bossing; Hydronephrosis; Hydrops fetalis; Hypertelorism; Hypodontia; Hypoplasia of penis; Hypoplastic scapulae; Hypospadias; Hypotelorism; Inguinal hernia; Joint hyperflexibility; Joint laxity; Lethal skeletal dysplasia; Long philtrum; Low-set ears; Macrocephaly; Microdontia; Micrognathia; Micromelia; Narrow chest; Osteoporosis; Pectus excavatum; Polycystic kidney dysplasia; Polydactyly; Postaxial hand polydactyly; Postaxial polydactyly; Prominent occiput; Pulmonary hypoplasia; Renal cyst; Renal hypoplasia; Respiratory insufficiency; Rhizomelia; Short distal phalanx of finger; Short foot; Short long bone; Short neck; Short palm; Short ribs; Short thorax; Sparse hair; Syndactyly; Telecanthus; Thoracic dysplasia; Urethrovaginal fistula; Uterus didelphys; Wide nose; Widely spaced teethEctodermal Dysplasia ; Heterotaxy ; Short-Rib Thoracic Dysplasia
WDR607q36.3100%gene with protein product615462Abdominal distention; Abnormal pelvis bone ossification; Abnormality of cardiovascular system morphology; Abnormality of pelvic girdle bone morphology; Abnormality of the clavicle; Abnormality of the metaphysis; Abnormality of the ribs; Abnormality of the sternum; Absent or minimally ossified vertebral bodies; Acetabular spurs; Ambiguous genitalia; Autosomal recessive inheritance; Brachydactyly; Cleft upper lip; Cone-shaped epiphysis; Congenital hepatic fibrosis; Cryptorchidism; Depressed nasal bridge; Disproportionate short-limb short stature; Epicanthus; Failure to thrive; Femoral bowing; Frontal bossing; Hydronephrosis; Hydrops fetalis; Hypoplasia of penis; Lethal skeletal dysplasia; Long philtrum; Macrocephaly; Micrognathia; Micromelia; Narrow chest; Pancreatic fibrosis; Polyhydramnios; Postaxial hand polydactyly; Postaxial polydactyly; Preaxial polydactyly; Pulmonary hypoplasia; Renal hypoplasia; Respiratory insufficiency; Short foot; Short long bone; Short palm; Short ribs; Short stature; Short thorax; Skeletal dysplasia; Syndactyly; Thoracic dysplasia; Urethrovaginal fistula; Uterus didelphys; Ventricular septal defect; Wide noseDisorders of Sex Development; Short-Rib Thoracic Dysplasia


The gene coverage data provided by GeneDx represent an estimate based on previous results, but the specific sequencing coverage data for the genes selected may vary from individual to individual, and cannot be predicted exactly. Changes to an approved gene list can only be made by contacting GeneDx directly at 888-729-1206 and asking to speak with a member of our Whole Exome Sequencing Laboratory.


  SUGGESTED CUSTOM SLICES  

Customize below OR enter Suggested Slice ID on printed requisition form
(e.g. 706 XomeDxSlice - Slice ID: CS-Albinism).

Suggested Slice IDSuggested Gene List Name
CS-AlbinismAlbinism
CS-AAAplastic Anemia
CS-AutoImmuneAutoimmune Disorders
CS-BBSBardet-Biedl Syndrome
CS-BMFBone Marrow Failure Syndromes
CS-CVIDCommon Variable Immune Deficiency
CS-CKUTCongenital Kidney and Urinary Tract (CKUT) Anomalies
CS-DSDDisorders of Sex Development
CS-EDEctodermal Dysplasia
CS-FAFanconi Anemia
CS-AnemiaHemolytic Anemia
CS-HeterotaxyHeterotaxy
CS-IBDInflammatory Bowel Disease
CS-MaleInfMale Infertility
CS-WWSMuscular dystropy-dystroglycanopathy (Walker-Warburg)
CS-NephroticNephrotic Syndrome
CS-ObesityObesity
CS-PPKCIPalmoplantar keratoderma plus congenital ichthyosis
CS-Primary ImmunodefPrimary Immunodeficiency
CS-RhabdoRhabdomyolysis
CS-SRTDShort-Rib Thoracic Dysplasia
CS-VACTERLVACTERL Association
CS-WSWaardenburg Syndrome