XomeDxSlice Tool

Now Available - NEW XomeDxSlice Xpanded – Custom slice testing with trio analysis for lists >150 genes.

INSTRUCTIONS (AND TIPS)

ENTER GENES BELOW AND CLICK "ADD GENES TO SLICE"

If cutting and pasting from another document, please be sure to list EITHER one gene symbol per line OR enter a comma-separated list.


OR

SEARCH BY GENE SYMBOL OR PHENOTYPE (HPO TERM)

You may also use this search to review average exome sequencing coverage by entering the gene symbol below.

SELECTED GENES FOR YOUR SLICE

What do you want to do?

Place an e-order of this Slice on a specific patient through the GeneDx Portal  
Obtain a Slice ID to order testing with a printed requisition form  
Only email the gene list to myself and/or others at this time  


 
Phenotypes
Cardiac arrest

Select all: Gene symbolChrAvg % covered at 10xLocus TypeNoteOMIMPrevious symbol(s)Phenotype(s)Slice(s)
CALM114q32.11100%gene with protein product114180CALML2Autosomal dominant inheritance; Cardiac arrest; Prolonged QT interval; Sudden death; Syncope; Ventricular tachycardia; Vertigo
KCNE311q13.4100%gene with protein product604433Autosomal dominant inheritance; Cardiac arrest; EMG abnormality; Episodic flaccid weakness; Episodic hypokalemia; Exercise-induced muscle fatigue; Increased intramyocellular lipid droplets; Mildly elevated creatine phosphokinase; Periodic hypokalemic paresis; Postprandial hyperglycemia; ST segment elevation; Ventricular fibrillation
KCNH27q36.199.72%gene with protein product152427LQT2Atrial fibrillation; Autosomal dominant inheritance; Bradycardia; Cardiac arrest; Heterogeneous; Palpitations; Prolonged QT interval; Shortened QT interval; Sudden cardiac death; Syncope; Torsade de pointes; Ventricular fibrillation
KCNJ511q24.3100%gene with protein product600734Abnormal circulating renin; Adrenal hyperplasia; Atrioventricular block; Autosomal dominant inheritance; Cardiac arrest; Congestive heart failure; Coronary artery atherosclerosis; Decreased circulating renin level; Glucocortocoid-insensitive primary hyperaldosteronism; Hyperaldosteronism; Hypertension; Hypokalemia; Paroxysmal atrial fibrillation; Prolonged QT interval; Pulmonary embolism; Syncope
NDUFB11Xp11.399.85%gene with protein product300403Abnormal cardiac septum morphology; Abnormal facial shape; Abnormal morphology of the nasolacrimal system; Abnormality of retinal pigmentation; Abnormality of the eyelashes; Agenesis of corpus callosum; Anophthalmia; Arrhythmia; Cardiac arrest; Congenital diaphragmatic hernia; Dermal atrophy; Dilated cardiomyopathy; Dilation of lateral ventricles; Erythema; Failure to thrive; Hyperpigmentation of the skin; Hypertrophic cardiomyopathy; Hypopigmented skin patches; Lacrimal duct atresia; Mandibular aplasia; Micrognathia; Microphthalmia; Midface retrusion; Muscular hypotonia of the trunk; Myopia; Nystagmus; Retrognathia; Sclerocornea; Seizures; Severe short stature; Strabismus; Ventricular fibrillation; Ventricular tachycardia; Vitritis; Wide nasal bridge; Wide nose; X-linked dominant inheritance
SCN5A3p22.2100%gene with protein product600163CMD1EArrhythmia; Atrial fibrillation; Atrial flutter; Atrial standstill; Atrioventricular block; Autosomal dominant inheritance; Autosomal recessive inheritance; Cardiac arrest; Complete heart block with broad QRS complexes; Congenital onset; Dilated cardiomyopathy; Dyspnea; Heterogeneous; Left anterior fascicular block; Left bundle branch block; Left posterior fascicular block; Palpitations; Paroxysmal atrial fibrillation; Premature atrial contractions; Prolonged QT interval; Reduced systolic function; Right bundle branch block; Sick sinus syndrome; Sinus bradycardia; Stroke; Sudden cardiac death; Sudden death; Supraventricular tachycardia; Syncope; Torsade de pointes; Ventricular escape rhythm; Ventricular extrasystoles; Ventricular fibrillationHeterotaxy
TANGO222q11.21100%gene with protein product616830C22orf25Acute rhabdomyolysis; Ataxia; Autosomal recessive inheritance; Cardiac arrest; Cerebral atrophy; Clonus; Drooling; Dysarthria; Elevated hepatic transaminases; Elevated plasma acylcarnitine levels; Elevated serum creatine phosphokinase; Gait ataxia; Gait disturbance; Generalized hypotonia; Hyperactive deep tendon reflexes; Hypothyroidism; Intellectual disability; Ketonuria; Lactic acidosis; Metabolic acidosis; Muscle weakness; Myoglobinuria; Myopathic facies; Neurodegeneration; Oral-pharyngeal dysphagia; Poor coordination; Ventricular fibrillationRhabdomyolysis
TSPYL16q22.1100%gene with protein product604714TSPYLAbnormality of metabolism/homeostasis; Abnormality of the eye; Abnormality of the voice; Ambiguous genitalia; Ambiguous genitalia, male; Apnea; Autosomal recessive inheritance; Bradycardia; Bronchospasm; Cardiac arrest; Cardiorespiratory arrest; Cryptorchidism; Death in infancy; Dysautonomia; Dysplastic testes; Feeding difficulties in infancy; Gastroesophageal reflux; Growth delay; Hypoplasia of penis; Hyporeflexia; Hypothermia; Laryngospasm; Myoclonus; Ophthalmoplegia; Partial development of the penile shaft; Scrotal hypoplasia; Sleep apnea; Staccato cry; Stridor; Testicular dysgenesis; Tongue fasciculationsDisorders of Sex Development


The gene coverage data provided by GeneDx represent an estimate based on previous results, but the specific sequencing coverage data for the genes selected may vary from individual to individual, and cannot be predicted exactly. Changes to an approved gene list can only be made by contacting GeneDx directly at 888-729-1206 and asking to speak with a member of our Whole Exome Sequencing Laboratory.


  SUGGESTED CUSTOM SLICES  

Customize below OR enter Suggested Slice ID on printed requisition form
(e.g. 706 XomeDxSlice - Slice ID: CS-Albinism).

Suggested Slice IDSuggested Gene List Name
CS-AlbinismAlbinism
CS-AAAplastic Anemia
CS-AutoImmuneAutoimmune Disorders
CS-BBSBardet-Biedl Syndrome
CS-BMFBone Marrow Failure Syndromes
CS-CVIDCommon Variable Immune Deficiency
CS-CKUTCongenital Kidney and Urinary Tract (CKUT) Anomalies
CS-DSDDisorders of Sex Development
CS-EDEctodermal Dysplasia
CS-FAFanconi Anemia
CS-AnemiaHemolytic Anemia
CS-HeterotaxyHeterotaxy
CS-IBDInflammatory Bowel Disease
CS-MaleInfMale Infertility
CS-WWSMuscular dystropy-dystroglycanopathy (Walker-Warburg)
CS-NephroticNephrotic Syndrome
CS-ObesityObesity
CS-PPKCIPalmoplantar keratoderma plus congenital ichthyosis
CS-Primary ImmunodefPrimary Immunodeficiency
CS-RhabdoRhabdomyolysis
CS-SRTDShort-Rib Thoracic Dysplasia
CS-VACTERLVACTERL Association
CS-WSWaardenburg Syndrome