XomeDxSlice Tool

Now Available - NEW XomeDxSlice Xpanded – Custom slice testing with trio analysis for lists >150 genes.

INSTRUCTIONS (AND TIPS)

ENTER GENES BELOW AND CLICK "ADD GENES TO SLICE"

If cutting and pasting from another document, please be sure to list EITHER one gene symbol per line OR enter a comma-separated list.


OR

SEARCH BY GENE SYMBOL OR PHENOTYPE (HPO TERM)

You may also use this search to review average exome sequencing coverage by entering the gene symbol below.

SELECTED GENES FOR YOUR SLICE

What do you want to do?

Place an e-order of this Slice on a specific patient through the GeneDx Portal  
Obtain a Slice ID to order testing with a printed requisition form  
Only email the gene list to myself and/or others at this time  


 
Phenotypes
Abnormal rapid eye movement sleep

Select all: Gene symbolChrAvg % covered at 10xLocus TypeNoteOMIMPrevious symbol(s)Phenotype(s)Slice(s)
CTSH15q25.199.97%gene with protein product116820CPSBAbnormal rapid eye movement sleep; Abnormality of vision; Cataplexy; Excessive daytime sleepiness; Hallucinations; Transient global amnesia
HCRT17q21.2100%gene with protein product602358Abnormal rapid eye movement sleep; Abnormality of vision; Autosomal dominant inheritance; Cataplexy; Excessive daytime sleepiness; Excessive daytime somnolence; Hallucinations; Heterogeneous; Hypnagogic hallucinations; Hypnopompic hallucinations; Insomnia; Narcolepsy; Paroxysmal drowsiness; Transient global amnesia
HCRT17q21.2100%gene with protein product602358Abnormal rapid eye movement sleep; Abnormality of vision; Autosomal dominant inheritance; Cataplexy; Excessive daytime sleepiness; Excessive daytime somnolence; Hallucinations; Heterogeneous; Hypnagogic hallucinations; Hypnopompic hallucinations; Insomnia; Narcolepsy; Paroxysmal drowsiness; Transient global amnesia
HLA-DQB16p21.3290.9%gene with protein productXomeDxSlice is not appropriate.604305HLA-DQBAbnormal blistering of the skin; Abnormal rapid eye movement sleep; Abnormality of vision; Achalasia; Autoimmunity; Cataplexy; Diabetes mellitus; Eczema; Erythema; Excessive daytime sleepiness; Excessive daytime somnolence; Hallucinations; Insomnia; Macule; Psoriasiform dermatitis; Recurrent infections; Transient global amnesia; Urticaria; Weight loss
HLA-DRB16p21.3297.56%gene with protein productXomeDxSlice is not appropriate.142857HLA-DR1BAbnormal blistering of the skin; Abnormal rapid eye movement sleep; Abnormality of vision; Arthralgia; Arthritis; Autoimmunity; Carious teeth; Cataplexy; Chest pain; Cough; Diabetes mellitus; Dyspareunia; Dysphagia; Dyspnea; Eczema; Elevated C-reactive protein level; Elevated erythrocyte sedimentation rate; Erythema; Erythema nodosum; Excessive daytime sleepiness; Excessive daytime somnolence; Fatigue; Fever; Flexion contracture; Gastroesophageal reflux; Hallucinations; Hypopigmented skin patches; Increase in T cell count; Insomnia; Joint swelling; Juvenile rheumatoid arthritis; Leukopenia; Lymphadenopathy; Lymphoma; Macule; Malabsorption; Mediastinal lymphadenopathy; Mucosal telangiectasiae; Muscle weakness; Narrow foramen obturatorium; Nausea and vomiting; Night sweats; Oliguria; Osteolysis; Psoriasiform dermatitis; Pulmonary fibrosis; Pulmonary infiltrates; Recurrent infections; Skin rash; Skin ulcer; Splenomegaly; Telangiectasia of the skin; Thrombocytopenia; Transient global amnesia; Urticaria; Uveitis; Weight loss; Xerostomia
MOG6p22.199.99%gene with protein product159465Abnormal rapid eye movement sleep; Abnormality of vision; Autosomal dominant inheritance; Cataplexy; Excessive daytime sleepiness; Hallucinations; Narcolepsy; Obesity; Transient global amnesiaObesity
P2RY1119p13.2100%gene with protein product602697Abnormal rapid eye movement sleep; Abnormality of vision; Cataplexy; Excessive daytime sleepiness; Hallucinations; Transient global amnesia
TNFSF41q25.1100%gene with protein product603594TXGP1Abnormal rapid eye movement sleep; Abnormality of vision; Cataplexy; Excessive daytime sleepiness; Hallucinations; Transient global amnesia
ZNF36510q21.272.45%gene with protein product607818Abnormal rapid eye movement sleep; Abnormality of vision; Cataplexy; Excessive daytime sleepiness; Excessive daytime somnolence; Hallucinations; Insomnia; Transient global amnesia


The gene coverage data provided by GeneDx represent an estimate based on previous results, but the specific sequencing coverage data for the genes selected may vary from individual to individual, and cannot be predicted exactly. Changes to an approved gene list can only be made by contacting GeneDx directly at 888-729-1206 and asking to speak with a member of our Whole Exome Sequencing Laboratory.


  SUGGESTED CUSTOM SLICES  

Customize below OR enter Suggested Slice ID on printed requisition form
(e.g. 706 XomeDxSlice - Slice ID: CS-Albinism).

Suggested Slice IDSuggested Gene List Name
CS-AlbinismAlbinism
CS-AAAplastic Anemia
CS-AutoImmuneAutoimmune Disorders
CS-BBSBardet-Biedl Syndrome
CS-BMFBone Marrow Failure Syndromes
CS-CVIDCommon Variable Immune Deficiency
CS-CKUTCongenital Kidney and Urinary Tract (CKUT) Anomalies
CS-DSDDisorders of Sex Development
CS-EDEctodermal Dysplasia
CS-FAFanconi Anemia
CS-AnemiaHemolytic Anemia
CS-HeterotaxyHeterotaxy
CS-IBDInflammatory Bowel Disease
CS-MaleInfMale Infertility
CS-WWSMuscular dystropy-dystroglycanopathy (Walker-Warburg)
CS-NephroticNephrotic Syndrome
CS-ObesityObesity
CS-PPKCIPalmoplantar keratoderma plus congenital ichthyosis
CS-Primary ImmunodefPrimary Immunodeficiency
CS-RhabdoRhabdomyolysis
CS-SRTDShort-Rib Thoracic Dysplasia
CS-VACTERLVACTERL Association
CS-WSWaardenburg Syndrome