Say hello to digital Patient Letters! Learn more >

Periodic Fever Syndromes Panel (7 genes)

New York
Approved


Genes

ELANE (ELA2), LPIN2, MEFV, MVK, NLRP3 (CIAS1), PSTPIP1, TNFRSF1A

Conditions

  • Chronic Infantile Neurologic Cutaneous and Articular Syndrome
  • Cyclic Neutropenia
  • Familial Cold Autoinflammatory Syndrome
  • Familial Cold Urticaria syndrome
  • Familial Hibernian Fever
  • Familial Mediterranean Fever
  • Hyper-IgD Syndrome
  • Majeed Syndrome
  • Muckle-Wells Syndrome
  • Neonatal Onset Multisystem Inflammatory Disease
  • TNF Receptor-Associated Periodic Syndrome

Clinical Utility

  • Confirmation of a clinical diagnosis
  • To assist in determining the most appropriate therapy, as the response to specific therapeutic modalities depends on the diagnosis
  • Recurrence risk
  • Carrier testing in at-risk family members
  • Prenatal diagnosis

Lab Method

  • Next-Gen Sequencing

Test Code

367

CPT Codes*

81404x1, 81479x1

ABN Required

No

Turnaround Time**

3 weeks

Preferred Specimen

2-5 mL Blood - Lavender Top Tube

Alternative Specimen

Buccal Swabs

*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

**Reporting times are typical and begin once the sample(s) are received at the GeneDx laboratory, but could be extended in situations outside GeneDx’s reasonable control.