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Autoimmune Lymphoproliferative Syndrome Panel

New York
Approved


Genes

CASP10, CASP8, FASLG, TNFRSF6

Conditions

  • Autoimmune Lymphoproliferative Syndrome (ALPS) Type 1A
  • Autoimmune Lymphoproliferative Syndrome Type IIA (ALPS IIA)
  • Autoimmune Lymphoproliferative Syndrome Type IIB (ALPS IIB)

Clinical Utility

  • Confirmation of the clinical diagnosis.
  • Differentiation from malignant forms of lymphoproliferation.
  • Distinguish sub-type of ALPS.
  • Development of an appropriate treatment plan for affected individuals.
  • Development of an appropriate medical surveillance plan for relatives at risk of lymphoma.

Lab Method

  • Next-Gen Sequencing
  • Deletion/Duplication Analysis

Test Code

T990

CPT Codes*

81479x1

ABN Required

No

Turnaround Time**

3 weeks

Preferred Specimen

2-5 mL Blood - Lavender Top Tube

Alternative Specimen

Buccal Swabs

*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

**Reporting times are typical and begin once the sample(s) are received at the GeneDx laboratory, but could be extended in situations outside GeneDx’s reasonable control.