Ovarian dysfunction

Forms and Documents

Test Details

BMP15, CYP17A1, CYP19A1, ESR1, FGFR1, FIGLA, FSHR, GDF9, KISS1, KISS1R, LHB, LHCGR, NOBOX, NR5A1, POR, PROK2, PROKR2, PSMC3IP, SEMA3A, TAC3, TACR3, WDR11
  • Molecular confirmation of a clinical diagnosis
  • To assist with decisions about treatment and management of individuals with POF
  • Testing of at-risk relatives for specific known mutation(s) previously identified in an affected family member
  • Prenatal diagnosis for known familial mutation(s) in at-risk pregnancies

Ordering

677
4 weeks
2-5 mL Blood - Lavender Top Tube
Buccal Swabs

Billing

81405x2, 81406x1, 81479x1
Yes
Yes
For price inquiries please email zebras@genedx.com

*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

References

  1. Persani et al., (2010) J Mol Endocrinol 45:257-279 (PMID: 20668067).
  2. Shelling (2010) Reproduction 140(5):633-641 (PMID: 20716613).
  3. Woad et al., (2006) Aust N Z J Obstet Gynaecol 46(3):242-244 (PMID: 16704481).
  4. Pirozzi et al., (2011) Am J Med Genet A 155:1803-1816 (PMID: 21739597).
  5. Willemsen et al., (2011) Clin Genet 80(3):214-225 (PMID: 21651511).
  6. ACOG Committee Opinion Number 469 (2010) Obstet Gynecol 116:1008-1010 (PMID: 20859177).
  7. Conte et al., (1994) J Clin Endocrinol Metab 78(6):1287-1292 (PMID: 8200927).
  8. Jones et al., (2006) Trends Endocrinol Metab 17(2):53-62 (PMID: 16480891).
  9. Lourenco et al., (2009) N Engl J Med 360:1-11 (PMID: 19246354).
  10. Bennett (2004) Pharmacogenomics 5(4):433-438 (PMID: 15165179).
  11. McConkie-Rosell et al., (2005) J Genet Couns14:249-270 (PMID: 16047089).
  12. Bouilly et al., (2011) Hum Mutat 32(10):1108-1113 (PMID: 21837770).
  13. Qin et al., (2007) Am J Hum Genet 81(3):576-581 (PMID: 17701902).
  14. Tiotiu et al., (2010) Hum Reprod 25(6):1581-1587 (PMID: 20364024)
  15. Laissue et al., (2006) Eur J Endocrinol 154(5):739-744 (PMID: 16645022).
  16. Zhao et al., (2008) Am J Hum Genet 82(6):1342-1348 (PMID: 18499083).
  17. Quaynor et al., (2013) N Engl J Med 368(2): 164-171 (PMID: 23841731).
  18. Bernard et al., (2017) J Clin Endocrinol Metab 102(1): 93-99 (PMID: 27754803).
  19. Caronia et al., (2011) N Engl J Med 364(3): 215-225 (PMID: 21247312).
  20. Topaloglu et al., N Engl J Med (2012) 366: 629-635 (PMID: 22335740).
  21. Valdez-Socin et al., (2014) Front Endocrinol 9;5: 109 (PMID: 25071724).
  22. Gianetti et al., (2010) J Clin Endocrinol Metab 96(6): 2857-2856 (PMID: 20332248).
  23. Hanchate et al., (2012) PLoS Genet 8(8): e1002896 (PMID: 22927827).
  24. Kim et al., (2010) Am J Hum Genet 87(4): 465-476 (PMID: 20887964).
  25. Fortuno and Labarta (2014) J Assist Reprod Genet 31(12): 1575-1585 (PMID: 25227694).
  26. Qin et al., (2015) Hum Reprod 21(6): 787-808 (PMID: 26243799).