Forms and Documents
- An individual with a personal history and family history of tumors associated with Li-Fraumeni syndrome (LFS), such as soft tissue sarcoma, osteosarcoma, brain tumors, breast cancer, adrenocortical carcinoma, etc., particularly if at least one is early-onset
- An individual with multiple primary cancers within the LFS-tumor spectrum, particularly if at least one is early-onset
- An individual with a personal history of a rare LFS-associated tumor, such as an adrenocortical carcinoma, choroid plexus carcinoma, rhabdomyosarcoma of embryonal anaplastic subtype, etc., regardless of age
- An individual with breast cancer diagnosed at age 30 or younger
- An unaffected individual with a family history suggestive of LFS (see above) when an affected individual is unavailable for his or her own genetic testing.
*Reporting times are typical, but could be extended in situations outside GeneDx's reasonable control.
**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
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- Bougeard et al., (2003) Oncogene 22:840-846.
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- Gonzalez et al., (2009) J Clin Oncol 27:1250-1256.
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- Li et al., (1988) Cancer Res 48:5358-5362.
- Tinat et al., (2009) J Clin Oncol 27(26):e108-e109.
- Varley et al., (2003) Hum Mutat 21:313-320.