Affected males have hypotrichosis with fine, sparse and light-colored scalp and body hair. Beard hair is often normal. Other features include a decreased ability to sweat, which often leads to severe heat intolerance, hypodontia and conical or peg shaped teeth. The facial features are characterized by dark pigmented skin around the eyes, saddle nose and full lips. The function of lacrimal, meibomian and other glands is defective and there is thick nasal secretion and cerumen. Absent or accessory nipples are not uncommon. Female carriers of this disorder may have some minor symptoms, including thin hair, patches of hypohidrosis, and abnormal dentition.