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Feingold Syndrome is characterized by a combination of congenital anomalies, most notably microcephaly, distal limb malformations, and esophageal/duodenal atresia. Approximately 85% of affected individuals have microcephaly, often associated with learning disabilities or mild mental retardation. Short middle phalanges of the 2nd and 5th fingers are the most common feature. Other limb malformations may include clinodactyly of the 2nd and 5th fingers, hypoplastic thumbs, restricted finger and elbow movement, and syndactyly of the 2nd/3rd and 4th/5th toes. Gastrointestinal atresia is found in almost 40% of affected individuals. Although esophageal atresia with or without tracheo-esophageal fistula is seen in only 25-30% of patients, Feingold syndrome may emerge as one of the more common forms of syndromic esophageal atresia. Less frequently reported clinical features include short palpebral fissures, broad nasal bridge, anteverted nostrils, micrognathia, ear abnormalities, cardiovascular anomalies (most commonly patent ductus arteriosus), renal and vertebral anomalies, deafness, and short stature. These features exhibit significant inter- and intra-familial variability. The constellation of anomalies observed in Feingold syndrome shows considerable overlap with the VATER/VACTERL association, most significantly esophageal/ duodenal atresia