Familial Cutaneous Malignant Melanoma

It is estimated that about 10% of melanoma is hereditary. Individuals with familial melanoma have a genetic predisposition to develop multiple clinically abnormal, histologically dysplastic, pigmented nevi distributed over both sun-exposed and sun-protected areas of the body. The age of onset tends to be earlier than in individuals with sporadic (non-hereditary) melanoma. Affected individuals also have an increased risk to develop ocular melanoma, and some families show a predisposition to pancreatic cancer.

Tests Available

Forms and Documents

Test Details

  • Identification of a hereditary susceptibility to malignant melanoma
  • Development of a clinical surveillance plan for early detection
  • Identification of at-risk family members


2 weeks
2-5 mL Blood - Lavender Top Tube
Buccal Swabs | Fibroblasts (separate charge for cell culture may apply)


81404x1, 81479x1
* For price inquiries please email zebras@genedx.com


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