Chromosomal Abnormalities

Forms and Documents

Test Details

  • For prenatal diagnostic samples: Fetal abnormalities detected by ultrasound, abnormal maternal serum screening test result, advanced maternal age, family history of chromosome abnormality, abnormal aCGH result requiring chromosome analysis for clarification, recurrent spontaneous abortions. Fetal tissue obtained after a miscarriage (products of conception) can also be submitted for chromosome analysis and/or aCGH.
  • For peripheral blood samples: Multiple congenital abnormalities with or without mental retardation/developmental delay; family history of chromosome abnormality; infertility; short stature; recurrent spontaneous abortions. Sometimes a skin or tissue biopsy may be used to provide material for chromosome analysis.

Ordering

2136
1-2 weeks
20 mL Amniotic Fluid
20 mg CVS|2 T25 flasks of cultured amniocytes|2 T25 flasks of cultured chorionic villi

*Reporting times are typical, but could be extended in situations outside GeneDx's reasonable control.

Billing

88235x1, 88267x1, 88280x1, 88291x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Forms and Documents

Test Details

  • For prenatal diagnostic samples: Fetal abnormalities detected by ultrasound, abnormal maternal serum screening test result, advanced maternal age, family history of chromosome abnormality, abnormal aCGH result requiring chromosome analysis for clarification, recurrent spontaneous abortions. Fetal tissue obtained after a miscarriage (products of conception) can also be submitted for chromosome analysis and/or aCGH.
  • For peripheral blood samples: Multiple congenital abnormalities with or without mental retardation/developmental delay; family history of chromosome abnormality; infertility; short stature; recurrent spontaneous abortions. Sometimes a skin or tissue biopsy may be used to provide material for chromosome analysis.

Ordering

A587
1-2 weeks
20 mg CVS
20 mL Amniotic Fluid|2 T25 flasks of cultured amniocytes|2 T25 flasks of cultured chorionic villi

*Reporting times are typical, but could be extended in situations outside GeneDx's reasonable control.

Billing

88235x1, 88267x1, 88261x1, 88291x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Forms and Documents

Test Details

  • For prenatal diagnostic samples: Fetal abnormalities detected by ultrasound, abnormal maternal serum screening test result, advanced maternal age, family history of chromosome abnormality, abnormal aCGH result requiring chromosome analysis for clarification, recurrent spontaneous abortions. Fetal tissue obtained after a miscarriage (products of conception) can also be submitted for chromosome analysis and/or aCGH.
  • For peripheral blood samples: Multiple congenital abnormalities with or without mental retardation/developmental delay; family history of chromosome abnormality; infertility; short stature; recurrent spontaneous abortions. Sometimes a skin or tissue biopsy may be used to provide material for chromosome analysis.

Ordering

1053
1-2 weeks
POC or Other Fetal Tissue

Billing

88230x1, 88262x1, 88291x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Forms and Documents

Test Details

  • Abnormal fetal ultrasound findings
  • Ambiguous karyotype results
  • Suspected deletion/duplication syndrome
  • Family history of known or suspected chromosome imbalances
  • Abnormal maternal serum screening
  • Advanced maternal age

Ordering

410
~2 weeks
20 mL Amniotic Fluid
20 mg CVS | 2 T25 flasks of cultured amniocytes | 2 T25 flasks of cultured chorionic villi | 3 Ug DNA Concentration

*Reporting times are typical, but could be extended in situations outside GeneDx's reasonable control.

Billing

81229x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

References

  1. Rickman L et al. Eur J Med Genet 48:232?240, 2005
  2. Sagoo GS et al. Genet Med 2009;11:139?46
  3. Hochstenbach R et al. Eur J Med Genet 2009;52:161?9
  4. ACOG Committee Opinion No. 446. Obstet & Gynecol 114:1161?1163, 2009
  5. Vialard F et al. Fetal Diagn Ther 25:277?284, 2009

Forms and Documents

Test Details

  • Multiple pregnancies

Ordering

437
1 week
10 mL Amniotic Fluid
20 mg CVS | 2 T25 flasks of cultured amniocytes | 2 T25 flasks of cultured chorionic villi | 3 Ug DNA Concentration

*Reporting times are typical, but could be extended in situations outside GeneDx's reasonable control.

Billing

81265x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

Forms and Documents

Test Details

  • Abnormal fetal ultrasound findings
  • Ambiguous karyotype results
  • Suspected deletion/duplication syndrome
  • Family history of known or suspected chromosome imbalances
  • Abnormal maternal serum screening
  • Advanced maternal age

Ordering

460
~2 weeks
20 mL Amniotic Fluid
20 mg CVS, 2 T25 flasks cultured amnioctyes, 2 T25 flasks of cultured chorionic villi, 3 ug DNA, POC or other fetal tissue

*Reporting times are typical, but could be extended in situations outside GeneDx's reasonable control.

Billing

81229x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

References

  1. Wapner, R.A. (2012) AJOG 206(1) Supplement:S2
  2. ACOG Committee Opinion No. 446. Obstet Gynecol 114:1161-1163, 2009.
  3. Vialard F et al. Fetal Diagn Ther 25:277-284, 2009.
  4. Rickman L et al. Eur  J Med Genet 48:232-­?240, 2005.

Forms and Documents

Test Details

  • For peripheral blood samples: Multiple congenital abnormalities with or without mental retardation/developmental delay; family history of chromosome abnormality; infertility; short stature; recurrent spontaneous abortions.

Ordering

0559
1-2 weeks
2-5 mL Blood-Sodium Heparin, Green Top Tube. Please note that samples received greater than 7 days after collection will be rejected and not used for analysis.

Billing

88230x1, 88262x1
Yes
Yes
For price inquiries please email zebras@genedx.com

**The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.