STAT3 Remaining Exons Sequencing

Forms and Documents

Test Details

STAT3
  • Confirmation of a clinical diagnosis
  • Prenatal diagnosis
  • Capillary Sequencing

Ordering

3122
3 weeks
2-5 mL Blood - Lavender Top Tube
Oral Rinse (30-40 mL)|Buccal Brushes

Billing

81479x1
No
Yes
  • 513 Abscess of lung and mediastinum
  • 680.x Boil
  • 288.1 Functional disorders of polymorphonuclear neutrophils, Chronic (childhood) granulomatous disease, Congenital dysphagocytosis, Job's syndrome, Lipochrome histiocytosis (familial), Progressive septic granulomatosis
  • 482.x Other pneumonia
  • 481 Pneumococcal pneumonia [Streptococcus pneumoniae pneumonia], Lobar pneumonia, organism unspecified
* For price inquiries please email zebras@genedx.com

References

  1. Minegishi Y et al., Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome, Nature 448:1058-1062, 2007
  2. Holland SM et al., STAT3 mutations in the Hyper-IgE syndrome, NEJM 357:1608-1619, 2007
  3. Renner ED et al., STAT3 mutation in the original patient with Job’s syndrome, NEJM 357:1667- 1668, 2007