Genetic Testing Company | The DNA Diagnostic Experts | GeneDx

In observance of Labor Day, GeneDx will be closed and will not accept specimens on Monday, September 7, 2015.  We will resume our normal schedule on Tuesday, September 8, 2015.  If you have any questions or inquiries, please call us at 301-519-2100 or email us at zebras@genedx.com.

FAS (TNFRSF6) Gene Sequencing

FORMS AND DOCUMENTS

TEST DETAILS

Genes:
FAS (TNFRSF6)
Disorders:
Clinical Utility:
  • Confirmation of the clinical diagnosis
  • Differentiation from malignant forms of lymphoproliferation and from other sub-types of ALPS
  • Identification of relatives carrying the TNFRSF6 mutation who may have less severe disease
  • Development of an appropriate treatment plan for affected individuals
  • Development of an appropriate medical surveillance plan for relatives at risk of lymphoma
Lab Method:
Capillary Sequencing

ORDERING

Test Code:
138
Turnaround Time:
6-7 weeks
Preferred Specimen:
2-5 mL Blood - Lavender Top Tube
Alternative Specimen:
Oral Rinse (30-40 mL), Dried Blood Spots

BILLING

CPT Codes:
81479x1
New York Approved:
No
ABN Required:
Yes
Billing Information:
View Billing Policy
ICD Codes:
  • 238.7: Other lymphatic and hematopoietic tissues
  • 202.x: Malignant neoplasms of lymphoid and histiocytic tissue, specific decimal required
  • 283: Autoimmune hemolytic anemias, Autoimmune hemolytic disease, Chronic cold hemagglutinin disease, Cold agglutinin disease or hemoglobinuria Hemolytic anemia
* For price inquiries please email zebras@genedx.com

REFERENCES

  1. Jackson C,.et al., (1999), Autoimmune lymphoproferative syndrome with defective Fas: genotype influences penetrance, Am. J. Hum. Genet. 64:1002-1004
  2. Vaishnaw, A, et al., (1999), The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations. J. Clin. Invest. 103: 355-363

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