In observance of Labor Day, GeneDx will be closed and will not accept specimens on Monday, September 7, 2015. We will resume our normal schedule on Tuesday, September 8, 2015. If you have any questions or inquiries, please call us at 301-519-2100 or email us at email@example.com.
DMP1 Gene Sequencing
FORMS AND DOCUMENTS
- Clinical Utility:
- Confirmation of the clinical diagnosis
- Differentiation from autosomal dominant and X-linked forms of the disease
- Determination of appropriate therapeutic approach
- Prenatal diagnosis in at-risk pregnancies
- Lab Method:
- Capillary Sequencing
- Test Code:
- Turnaround Time:
- 6-8 weeks
- Preferred Specimen:
- 2-5 mL Blood - Lavender Top Tube
- Alternative Specimen:
- Oral Rinse (30-40 mL), Dried Blood Spots
- CPT Codes:
- New York Approved:
- ABN Required:
- Billing Information:
- View Billing Policy
- ICD Codes:
- 275.3: Disorders of phosphorus metabolism, Familial hypophosphatemia, Hypophosphatasia, Vitamin D-resistant: osteomalacia rickets
- 268.2: Osteomalacia, unspecified
- Feng, J.Q., et al., Loss of DMP1 Causes Rickets and Ostomalacia and Identified a Role for Osteocytes in Mineral Metabolism, Nat Genet 38(11): 1310-1315 (2006).
- Lorenz-Depiereux, B., et al., DMP1 Mutations in Autosomal Recessive Hypophosphatemia Implicate a Bone Matrix Protein in the Regulation of Phosphate Homeostasis, Nat Genet 38(11):1248-1250 (2006).
- Farrow et al. The role of DMP1 in autosomal recessive hypophosphatemic rickets. J Musculoskelet Neuronal Interact 7(4):30-312 (2007).