Genetic Testing Company | The DNA Diagnostic Experts | GeneDx

BrS Sequencing Panel

FORMS AND DOCUMENTS

TEST DETAILS

Genes:
CACNA1C, CACNB2, GPD1L, KCNE3, SCN1B, SCN3B, SCN5A
Disorders:
Clinical Utility:
  • Confirmation of a clinical diagnosis in Risk assessment of asymptomatic family members of a proband with Brugada syndrome
  • Recurrence risk calculation
  • Differentiation of hereditary BrS from other acquired or genetic heart conditions
  • Prenatal diagnosis in families with a known mutation
Lab Method:
Next-gen Sequencing
Clinical Sensitivity:
24%-41%

ORDERING

Test Code:
384
Turnaround Time:
8 weeks
Preferred Specimen:
2-5 mL Blood - Lavender Top Tube

BILLING

CPT Codes:
81404x1, 81406x1, 81407x1
New York Approved:
Yes
ABN Required:
Yes
Billing Information:
View Cardiology Billing Policy
ICD Codes:
  • 746.89: Other Atresia of cardiac vein, Hypoplasia of cardiac vein, Congenital: cardiomegaly diverticulum, left ventricle pericardial defect
  • 427.9: Cardiac dysrhythmia, unspecified Arrhythmia (cardiac) NOS
  • 427: Cardiac dysrhythmias
  • 426.9: Conduction disorder, unspecified Heart block NOS, Stokes-Adams syndrome
* For price inquiries please email zebras@genedx.com

REFERENCES

  1. GeneReviews: Brugada syndrome. Brugada R, Brugada P, Brugada J and Hong K. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=brugada Accessed August 23, 2009.
  2. Fowler SJ and Priori SG. Curr Opin Cardiol. 24:74-81, 2008. (PubMed: 19102039)
  3. Ekhardt L. J Cardiovasc Electrophysiol. 18:422-424, 2007. (PubMed: 17286563)
  4. Hedley P et al., Hum Mutation. 30:1-11, 2009 (PubMed: 19606473)
  5. Bennett S. Pharmacogenomics. 5(4):433-8, 2004 (PubMed: 15165179)

Back To Top