GeneDx arrays now detect copy number variations and UPD.

GeneDx offers full-service molecular cytogenetic testing, including a custom-designed whole-genome array CGH test. In addition, an economical targeted array CGH test is available to rule out 65 common or novel genomic disorders as well as terminal and pericentromeric chromosomal rearrangements. Supplementing these tests is a FISH service that can be requested as a stand-alone test for genomic disorders or specific segmental aneuploidies, or as a follow-up test for parents of a proband with a positive array CGH result.

GeneDx also offer prenatal array CGH testing. For more information, click here.

Please select the options below to learn more about the GeneDx molecular cytogenetics offerings. Contact GeneDx directly if you would like to discuss specific details or you require additional clarification.

A description of the GeneDx molecular cytogenetic service can be downloaded here.

GenomeDx – cytogenetic whole-genome array CGH 
        Test information
        How to order

FISHonChipDx – a low-cost targeted array CGH test
        Test information
        How to order

FISH – A library of FISH probes are available for deletion/duplication syndromes and subtelomeres
       Test information
       How to order

Prenatal array CGH – GeneDx also offer prenatal array CGH testing. For more information, click here.

 Genome analysis  – Array CGH reports from GeneDx contain data that can be used to explore genomic regions of interest in the UCSC genome browser here. Sign in with the username "GenomeDx" and password "report". Enter the sequence coordinates from the report in the format "chr#:xxxxx-xxxxx". Array probes are shown on the top half.

 Array CGH guide for physicians and patients

The ISCA consortium
GeneDx participates in the International Standard Cytogenomic Array (ISCA) consortium. Anonymized array CGH data and clinical information may be submitted to a HIPAA-compliant, de-identified database as part of the National Institutes of Health's effort to improve diagnostic testing and enhance our understanding of the relationships between genetic changes and clinical symptoms. Visit the consortium website here. Confidentiality and full anonymity of each submission is maintained. Please use the current GeneDx molecular cytogenetics test requisition and consent forms when requesting testing. If these GeneDx forms are not sent with the submitted specimen, array data will be anonymized and submitted to the ISCA database. If you wish not to have genomic information derived from your submitted sample sent to the database, please email iscaoptout@genedx.com