Genetic Testing Company | The DNA Diagnostic Experts | GeneDx

Oncology Genetics

 

Videos-1  

 

Oncology Genetic Testing Services

Over the past ten years, research has identified many genes associated with hereditary cancers. Some of these genes play a role in more than one type of cancer, and in most types of cancer several genes can cause the cancer. GeneDx has developed comprehensive panels to facilitate testing of all the important genes associated with inherited cancer, in a manner that provides rapid and accurate results and at typically no additional cost as compared to testing for a single gene. For a copy of our gene summary and lifetime risk chart, click here

Please download our Family History Questionnaire to assist in determining if the patient’s personal or family history is suggestive of a hereditary cancer syndrome and if they are a candidate for genetics follow-up.

Test

Gene(s)

Further Information

BRCA1 and BRCA2 Sequencing and Del/Dup Analysis

BRCA1, BRCA2

 Test Info Sheet Clinician Guide
 Patient Guide Spanish Patient Guide
 LOMN 
BRCA1 and BRCA2 SequencingBRCA1, BRCA2
  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 
BRCA1 and BRCA2 Del/DupBRCA1, BRCA2
  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 

BRCA1 and BRCA2 Ashkenazi Founder Mutation

BRCA1/2 Targeted Mutation Analysis (BRCA1 c.68_69delAG [also known as 185delAG or 187delAG], c.5266dupC [also known as 5382insC or 5385insC] and BRCA2 c.5946delT [also known as 6174delT])

  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 

Comprehensive Cancer Panel (29 Genes)

APC, ATM, AXIN2, BARD1,  BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, FANCC, MLH1, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53, VHL, XRCC2

  Test Info Sheet  Lifetime Risk Chart
LOMN 
High/Moderate Risk Panel (20 Genes)APC, ATM, BMPR1A, BRCA1, BRCA2, CDH1, CDKN2A, CHEK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, PALB2, PMS2, PTEN, SMAD4, STK11, TP53, VHL
  Test Info SheetLOMN
Breast Cancer High Risk Panel (6 Genes)BRCA1, BRCA2, CDH1, PTEN, STK11, TP53
  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 

Breast Cancer High Risk Panel and PALB2 (7 Genes)

BRCA1, BRCA2, CDH1, PALB2, PTEN, STK11, TP53 
  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide

 

Breast Cancer High/Moderate Risk Panel (9 Genes)

ATM, BRCA1, BRCA2, CDH1, CHEK2, PALB2, PTEN, STK11, TP53

  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
Breast/Ovarian Cancer Panel (21 Genes)ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, FANCC, MLH1, MSH2, MSH6, NBN, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, TP53, XRCC2
  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 

Lynch/Colorectal High Risk Panel (7 Genes)

APC, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2

  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 
Colorectal Cancer Panel (16 Genes)APC, ATM, AXIN2, BMPR1A, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, SMAD4, STK11, TP53
  Test Info Sheet  Clinician Guide
  Patient Guide Spanish Patient Guide
LOMN 

MSH2 Exon 1-7 Inversion Analysis

MSH2

  Test Info Sheet

Pancreatic Cancer Panel (16 Genes)

APC, ATM, BRCA1, BRCA2, CDK4, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, TP53, VHL, XRCC2

  Test Info Sheet  Clinician Guide
  Patient GuideLOMN

Endometrial Cancer Panel (11 Genes)

BRCA1, BRCA2, CHEK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, PMS2, PTEN, TP53

  Test Info Sheet  Clinician Guide
  Patient GuideLOMN

Familial Cutaneous Malignant Melanoma (2 Genes)

 CDKN2A/p16, CDK4   Test Info Sheet

Rest of Comprehensive Cancer Panel (if subpanel negative)

 

  Test Info Sheet

LOMN

 

 

OncoGeneDx Custom Panel 

TestGene(s)Further Information
Custom PanelAPC, ATM, AXIN2, BARD1,  BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, FANCC, MLH1, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53, VHL, XRCC2

 Test Info Sheet

LOMN

 

 

Other Inherited Cancers 

TestGene(s)Further Information
Birt-Hogg-Dube Syndrome FLCN  Test Info Sheet
Bloom Syndrome BLM  Test Info Sheet
Carney Complex PRKAR1A  Test Info Sheet
Gorlin Syndrome PTCH1  Test Info Sheet
Hereditary Leiomyomatosis and Renal Cell Cancer FH  Test Info Sheet
Hyperparathyroidism-Jaw Tumor Syndrome CDC73  Test Info Sheet
Juvenile Polyposis Syndrome BMPR1A, SMAD4  Test Info Sheet
Li-Fraumeni Syndrome TP53  Test Info Sheet
Multiple Endocrine Neoplasia, Type 1 MEN1  Test Info Sheet
Multiple Endocrine Neoplasia, Type 2A and 2B RET  Test Info Sheet
PTEN Hamartoma Tumor SyndromePTEN  Test Info Sheet
Peutz-Jeghers SyndromeSTK11  Test Info Sheet
Von Hippel-Lindau SyndromeVHL  Test Info Sheet

Back To Top